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Tiwari and Chopra 2012)

[11] By adhering to these precautions, one can safely use bacteriostatic water to prepare injections without causing harm from the diluent itself

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Prolonged toxicity after amitriptyline overdose in a patient deficient in CYP2D6 activity

This limitation reflects a broader gap in the field: most randomized controlled trials and systematic reviews focus on major depressive disorder or depressive symptoms in heterogeneous populations, without separate analyses for distinct presentations like vascular depression, treatment-associated depressive states, or mood disturbances in the context of specific medical conditions