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Immunocytochemical localization of glutathione-insulin transhydrogenase in the pancreas, kidney and liver of normal and streptozotocin-diabetic rats and of lean and obese (ob/ob) mice

4 (November): 60316

Beyond direct radical trapping, elevated BH4 levels can also promote the synthesis of CoQ 10 (104), further enhancing ferroptosis resistance

A significant number of free radicals are generated during Phase 1, which can result in liver damage if adequate antioxidants (especially glutathione) are not available to quench them

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