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Description
Originally developed as a tanning agent (acting via MC1R receptors), it also binds to melanocortin receptors in the brain (particularly MC3R and MC4R) that influence sexual function
[DOI] [PubMed] [Google Scholar] (70).Matsui TA, Murata H, Sakabe T, Sowa Y, Horie N, Nakanishi R, Sakai T, Kubo T

In one study, the cell-to-cell interaction between HUVEC and QG90 cell, a tumor cell line derived from human small cell carcinoma of the lung expressing sialyl-LewisX antigen was studied, and it was found that IL-1 was able to induce the attachment of cancer cells to HUVEC

Yan, L., Li, J

Merugu R, Garimella S, Balla D, Sambaru K (2015) Synthesis and biological activities of pyrimidines: a review
