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Mice and humans that lack or overexpress MYOC have normal aqueous drainage and do not develop high IOP whereas mice expressing the human Tyr437His mutation in the olfactomedin domain develop elevated IOP and optic nerve damage that mirrors human glaucoma (21)

A similar observation has been cited earlier, where Salganik and peers experimentally revealed that dietary antioxidants had no impact on brain tumor growth, or could worsen the outcome [242]

It has been suggested that cyclical fluctuations in circulating steroid hormone levels can influence encoding and recall of emotional stimuli, and therefore may play a role in the expression of post-traumatic stress disorder (PTSD) symptomology (224, 225)

Arch Endocrinol Metab (2018) 62:54551

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