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Cardiac myocyte-specific HIF-1alpha deletion alters vascularization, energy availability, calcium flux, and contractility in the normoxic heart

[PubMed] [Google Scholar] Gu Y, Dee CM, Shen J

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These studies shown that alkaloids have great potential for the treatment of cardiovascular diseases by regulating the cellular autophagy pathway and that plant alkaloids and their derivatives can improve vascular function and cardiomyocyte function to play a cardioprotective role and can be used as a novel therapeutic tool in the treatment of chronic cardiovascular diseases