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In contrast, modified NADs typically require carriers to enter target cells and reach specific intracellular locations

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It should be noted that the studies performed using edited sequences (Emir et al., 2011, Hupfeld et al., 2021, Lally et al., 2016, Suri et al., 2017) used long TEs, and therefore, possible age-related differential changes in T2 relaxation time of GSH relative to the water or creatine quantitation reference could have confounded estimations of age-related concentration differences

demonstrated that 4-HNE can modulate the expression of antioxidant enzymes in mouse keratinocytes through various mechanisms

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