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19 , e11503 (2023)

X-ray Fluorescence Microscopy Sample preparation - Elemental mapping Specimens were prepared for XFM using previously described protocols 51, 52

Sirtuin modulation Modulating sirtuin activity by targeting NAD + -dependent deacylation may hold therapeutic potential for impacting mitochondrial homeostasis and other cellular pathways related to aging and disease

[DOI] [PMC free article] [PubMed] [Google Scholar] 153.Schelshorn DW, Schneider A, Kuschinsky W, Weber D, Krger C, Dittgen T, Brgers HF, Sabouri F, Gassler N, Bach A, Maurer MH

The process of protein denaturation is defined as the loss of protein function due to the application of external stress which disrupts the protein structures and folding