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With the continuous development of inhalation therapy, novel inhalation therapeutic techniques have made great progress in PF intervention, especially using MPs/NPs-mediated delivery, which has reached the preclinical stage

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Immunotherapy leverages the intrinsic immune system of the patient to engender efficacious therapeutic responses, while chemotherapy holds the potential to overturn the immunosuppressive microenvironment of the tumor, thereby amplifying immunogenic effects and fostering anti-tumor reactions

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It has been recently redefined by the International Association for the Study of Pain as a pain caused by lesion or disease of the somatosensory system and it may appear in a wide range of conditions

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