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3.1.3 Chemotherapy induces long-term (LT)-BM injury by reducing the self-renewal and proliferation ability of HSCs But in certain cases, thrombocytopenia persists and does not recover even in the subsequent chemotherapy cycle, and these patients experience LT-BM injury after chemotherapy due to HSC damage [66]

doi: 10.1111/codi.15113 Samantha Gillenwater, Feliipe Martinez, Ian Drexler, Christine Girard, Anas Hadeh, Farbod N

The changes are essentially those of a lentigo simplex occurring on a mucosal surface [8, 9]

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