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Sadrkhanloo M, Entezari M, Orouei S, Zabolian A, Mirzaie A, Maghsoudloo A, et al

Time course of oxidant markers and antioxidant defenses in subgroups of amyotrophic lateral sclerosis patients

PPAR- ligands upregulate transcription of genes that oppose myofibroblast differentiation by interfering with TGF-1 signaling via the Smad pathway in some cell types and suppress the production of pro-inflammatory cytokines and chemokines by various cell types by negatively affecting the nuclear transcriptional factor NF-B 21

At least three mice were recorded from each condition

In conclusion, modulating SOD expression or activities may enhance treatment efficacy