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It is characterized by perioral and mucocutaneous pigmentations, gastrointestinal polyposis, and an increased risk of cancer in adulthood.61 Pigmentations are seen in approximately 95% of the patients and constitute an early clinical sign, before any gastrointestinal symptoms

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Evidence suggests a link between prolonged MT2 use (over one month) combined with other tanning methods, such as sunbeds, and the development of rapidly changing moles or skin cancer [22, 23]

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