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Description
Conjugates of catecholamines with cysteine and GSH in Parkinsons disease: Possible mechanisms of formation involving reactive oxygen species

Table of Contents Overview Forms and Bioavailability Evidence for Benefits Recommended Dosing Safety and Side Effects Drug Interactions Dietary Sources References Overview Glutathione (GSH) is a tripeptide composed of three amino acids cysteine, glutamic acid, and glycine and is the most abundant intracellular antioxidant in the human body [1][2]

The failure of normal cellular processes that occur in relation to the aging process are also believed to contribute to the increased vulnerability of DA neurons (Schapira and Jenner, 2011

Tissue weights of liver, adipose tissue, and skeletal muscle were also comparable between groups (Supplemental Figure 1, IN)

Glutathione Together with glutaredoxins (Grx), GSH acts to reduce disulfide bonds and is, in turn, oxidized to glutathione disulfide (GSSG), which is reduced by NADPH-dependent glutathione reductase
