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Tirzepatide (the GIP-plus-GLP-1 dual agonist) has demonstrated superior weight loss compared to semaglutide monotherapy in SURMOUNT trials, with mean weight loss of up to 22.5% over 68 weeks

Renal failure and/or hepatic failure : Follow phenobarbital levels and re-dose accordingly

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Organic acid metabolism disorders have been linked to the occurrence of epileptic seizures

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