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It creates additive and potentially synergistic suppression of appetite through parallel circuits

10.3390/ijms22020654 [DOI] [PMC free article] [PubMed] [Google Scholar] 100.Sun S, Zhang Q, Li M, Gao P, Huang K, Beejadhursing R, Jiang W, Lei T, Zhu M, Shu K (2020) GDNF promotes survival and therapeutic efficacy of human adipose-derived mesenchymal stem cells in a mouse model of Parkinsons disease

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For example, activation of the MAPK pathway can upregulate DNA repair factors such as XRCC1 and RAD51, thereby enhancing resistance to agents like mitomycin C [64]

doi: 10.1016/s0029-7844(99)00305-1