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The combination of dehydration (from both the medication and alcohol), GI irritation, disrupted sleep, and potential blood sugar instability creates a hangover experience that is disproportionate to the amount consumed

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Cells were incubated for 24 h (RSL3, ML162, IKE, STS) or 48 h (ML210), where indicated, IACS-010759 (2 ), Antimycin (0.5 ), Oligomycin (2 ), FCCP (2 ), mitoquinone (0.25 ), SKQ1 (0.1 ), Ferrostatin (2 ), Z-VAD-FMK (50 ), Nec-1 (10 ) were also delivered to the cells

Chen et al , 2000)