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The metabolites derived from glutaminolysis lead to the accumulation of TCA cycle intermediates, such as succinate, fumarate, and malate

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Quantification of calcium signal transmission from sarco-endoplasmic reticulum to the mitochondria

Of particular importance is the fact that the GPX4 synthesis and function, intracellular iron homeostasis, and lipid peroxidation clearing can all be mediated by Nrf2 target genes

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