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While derivatization techniques significantly improve the sensitivity and accuracy of carnitine detection, they are not without drawbacks, such as the potential for incomplete reactions, additional synthetic steps prior to separation, and the challenge of separating derived from original analytes due to residual derivatization interference (Lipka et al., 2019)

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The expression and functional role of nicotinic acetylcholine receptors in rat adipocytes

Potential Adverse Effects We note that oral LC appeared to be fairly well tolerated throughout most of this review, with no significant differences between the experimental and control groups