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In a recent study, the lifespan of human mesenchymal stem cells obtained from aged participants was prolonged, by lengthening telomere and increasing the expression of the hTERT gene, following the use of l-carnitine (0.2 mM) for two days [71]

While L-carnitine is generally well-tolerated with mild potential side effects like gastrointestinal upset, its safety profile requires careful consideration, particularly regarding long-term use and its profound interaction with the gut microbiome

Beyond dose optimization, combining L-carnitine with nutrients or drugs may synergistically enhance its multi-target metabolic effects by regulating mitochondrial function, fatty acid oxidation, and insulin signaling

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Der Krper stellt L-Carnitin in der Leber und in den Nieren her, aber bei Vegetariern, lteren Erwachsenen oder Menschen mit bestimmten Gesundheitszustnden kann der Spiegel niedrig sein