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This is because, in autism, doctors are treating low B12 in the brain

Neurological symptoms represent a significant concern with B12 deficiency and may include: Paraesthesia (pins and needles) in the hands and feet Difficulty with balance and coordination Memory problems or cognitive changes Mood disturbances , including depression or irritability Glossitis (sore, red tongue) and mouth ulcers Haematological manifestations of B12 deficiency include megaloblastic anaemia , characterised by the production of abnormally large, immature red blood cells

The timeline for such developments typically extends 2-3 years beyond Phase 3 trial completion, placing potential regulatory milestones in the 2027-2028 timeframe