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All reactions were repeated for 3 wells and averaged

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Research demonstrates that regular exercise increases the spontaneous firing frequency of layer 5 pyramidal neurons in the motor cortex, intensifies their response to motor input, and accelerates their reaction speed during movement initiation (Destexhe and Marder, 2004)

Hypo-crotonylation of methylenetetrahydrofolate dehydrogenase 1 is suggested to impair ferroptosis by increasing protein levels of SLC7A11 and GPX4 as well as the GSH:GSSG ratios [326]