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Hypoxia not only manifests as the direct effect of insufficient oxygen supply to tissues, but the microenvironmental disturbances it triggers are often accompanied by significant oxidative stress, constituting a core factor exacerbating pathological damage [5]

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Among SCFAs, butyrate is considered the most beneficial

Muscle Activation Patterns Altered muscle activation patterns, particularly in the quadriceps and hamstrings, have been implicated in increasing ACL load