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Given that the majority of these studies were conducted in Western populations, further research in diverse ethnic groups is warranted

A24881) according to the manufacturer's protocol (Thermo Fisher Scientific, Inc.)

"In REDEFINE 1, CagriSema provided weight loss in the highest range of efficacy observed with existing weight loss interventions.Investigators were allowed some flexibility in dose adjustments to balance efficacy and safety, but regardless of dose adjustments participants lost significant weight

doi: 10.1136/jnnp-2014-309601 81

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