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These isomers also inhibit DNA/protein synthesis, promote differentiation and apoptosis, and reverse drug resistance [209], resulting in a synergistic effect greater than the sum of individual actions

JAMA 301 , 3951 (2009)

Figure 2 2.1.1 Pro-ferroptotic drivers: ACSL4 and iron Acyl-CoA synthetase long-chain family member 4 (ACSL4) is key determinant of ferroptosis sensitivity

Population-based surveillance for acute liver failure

The conversion of superoxide anions into hydrogen peroxide, before subsequently metabolized into water by catalase and glutathione (GSH) peroxidase, is facilitated by the metalloprotein superoxide dismutase (SOD)
