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However, further research has revealed that the development of some diseases is intricately regulated by redox signaling pathways (Table 1), suggesting that simplistic antioxidant therapy might exacerbate these conditions (Table 2)

Intracellular signaling pathway regulation of myelination and remyelination in the CNS

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Barlow S, Chesson A, Collins J et al (2005) Opinion of the scientific committee on a request from EFSA related to a harmonised approach for risk assessment of substances which are both genotoxic and carcinogenic