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While its strength in a high-coverage of predicted reactions, only a very small portion of them can be experimentally validated in organisms of interest

Cox, L., Compalati, E., Kundig, T

Cysteine oxidation promotes a post-translational modification of the GR that impairs its nuclear expression and binding to the glucocorticoid consensus and modifies the GR protein by decreasing available sulfhydryl groups and decreasing nuclear GR expression and activity [20]

It also plays roles in neurotransmitter regulation, skin tone, and mitochondrial health