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Additionally, circadian rhythms play a crucial role in the development of kidney fibrosis, a hallmark feature of CKD and other renal pathologies (Stow and Gumz, 2011a

Clin Cancer Res 13(9):25372540 Rzymski T, Milani M, Pike L, Buffa F, Mellor HR, Winchester L et al (2010) Regulation of autophagy by ATF4 in response to severe hypoxia

According to the KEGG enrichment analysis, the DEGs are chiefly enriched in the JAK-STAT signaling pathway, Th1 and Th2 cell differentiation, and the IL-17 signaling pathway