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Alpha Arbutin Targets uneven skin tone

Furthermore, it has been found that in HaCaT stimulated by proinflammatory cytokines (IL-17A, IL-17F, IL-1, TNF-, IL-6, IL-22), activation of the cPLA2 isoform increases the generation of anti-inflammatory N-acylethanolamines (NAEs), which alleviate epidermal hyperplasia, skin swelling, and reduce the expression of psoriatic markers, such as S100A9 proteins [60]

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[103] Yamada N, Matsushima-Nishiwaki R, Masue A, Taguchi K, Kozawa O

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