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[DOI] [PMC free article] [PubMed] [Google Scholar] 92.Flier JS, Maratos-Flier E

Although larger, controlled trials are necessary to establish LCs efficacy, its excellent safety profile and existing evidence support its potential as a novel treatment option for psychiatric and neurological disorders

Moreover, it is not known if S-5-HT mediated the effects of L-carnitine on fatigue, as it is possible that L-carnitine could have effects unrelated to S-5-HT that could reduce fatigue and in parallel promote increased synthesis of peripheral 5-HT

Application : coffee before training + L-carnitine 30 min before