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Increasing dietary fiber, staying well hydrated, and light daily movement like walking can address this effectively

133 One observational study reported that 92% of patients experienced clinically significant improvement (25 mg daily titrated up to 75 mg daily over several weeks)

however, this study had significant limitations, including no control group, and a small sample size (12 participants)

UM-SCC6 was a kind gift from Peking Union Medical University and cultured in DMEM/High Glucose medium (Hyclone, Logan, UT, USA)
