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Then, have a colleague check it

conducted their experiments on Hmox1 -deficient mice

doi: 10.1016/j.jpag.2014.05.005 95

Shock 27:134138 Grand J, Meyer AS, Kjaergaard J, Wiberg S, Thomsen JH, Frydland M, Ostrowski SR, Johansson PI, Hassager C (2020) A randomised double-blind pilot trial comparing a mean arterial pressure target of 65 mm Hg versus 72 mm Hg after out-of-hospital cardiac arrest

this finding was associated with a decreased intracellular NAD + /NADH ratio and decreased SIRT3 activity accompanied by increased expression of CD38, a NAD-degrading enzyme, in the kidneys of Zucker diabetic fatty rats (Ogura et al., 2018)