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A possible explanation for this is the overexpression of RCAN1 in DS

[DOI] [PubMed] [Google Scholar] 41.Gjurasin M, Miklic P, Zupancic B, Perovic D, Zarkovic K, Brcic L, et al

doi: 10.1128/AEM.67.8.3630-3635.2001

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Consider supplementation if dietary intake seems inadequate
