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The needle should be inserted at a slight angle through the septum center, and an equivalent volume of air should be injected into the vial before withdrawing liquid to prevent vacuum formation

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Prior to eventual internalization by distant immune cells, the formation of MVs, which also contain important immune-cell receptors and inhibitory complement receptors, may contribute to an immune or tolerogenic microenvironment for MM cells in the bone marrow (BM) niche [25] [26]

Per-component check at 0.10 mL: each dose is 1/30th of the vial (0.10 mL of 3 mL)

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