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The human gut microbiome is primarily composed of two dominant major bacterial phyla, Bacteroidetes and Firmicutes, composing 90% of the total gut bacteria with the remaining 10% represented by other phyla including Actinobacteria, Proteobacteria, Fusobacteria, and Verrucomicrobia

Alteration of the gut microbiota in tumor necrosis factor- antagonist-treated collagen-induced arthritis mice

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This can lead to blistering, severe pain, and skin damage