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doi: 10.1016/j.envint.2019.105057

Nothing unusual here, but understanding each step helps set realistic expectations

Although the TZDs were first marketed due to their ability to improve insulin sensitivity, they have since been shown to increase mitochondrial functions both in vitro and in vivo

Future studies need to focus more on validating the inductive effect of TMAO on ferroptosis in the in vivo OA models and human chondrocytes

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