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it mainly activates AMPK through energy consumption and is involved in the regulation of multiple network mechanisms (17)
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For the analysis, we selected genes that encode key MeOH-metabolizing enzymes ( ADH1, ALDH2, CAT, CYP2E1 , and ADH5 ) and NRF2, which is encoded by the NFE2L2 gene and is a well-known sensor of oxidative stress (Prasad, 2016)
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The redox state of the GSH/GSSG couple can serve as an important indicator of redox environment (2931), and changes in this couple correlate with multiple cellular processes, including cell differentiation (3237), cell proliferation (3237), and cell apoptosis (3842)
