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This pathological iron overload provides a continuous substrate for the Fenton reaction, constituting a fundamental and persistent risk factor driving lipid peroxidation and inducing ferroptosis (Zhang Y

Historically, the male reproductive tract was viewed as a sterile compartment, but modern high-throughput sequencing technologies have revealed that semen and prostatic fluid harbor unique low-biomass microbial communities

Although increased IL-5 has been detected in patients sputum, anti-IL-5 therapies are not effective in preventing exacerbations, highlighting that the mechanism by which eosinophils contribute to COPD is not yet to be understood [25]

The relationship of these metformin longevity response elements to each other and their hierarchy in the biological response to biguanides remains unknown

Yeast also require either a functional TrxR1 or functional Gsr system for survival