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S3), with two reporting higher GSH levels in brain (Choi et al., 2015, Dairy Intake, 0000) and in blood (The Safety, 0000, Xue et al., 2022) following dietary supplements intake (i.e., RiaGev, dairy food), thereby indicating that an increase in GSH levels is possible post-intervention in human

Iron homeostasis imbalance, leading to iron overload and subsequent ferroptosis, can damage the synovium, cartilage, and extracellular matrix (ECM), playing a crucial role in OA progression