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The ethanol produced by Klebsiella pneumoniae and Escherichia coli under anaerobic conditions can increase the activity of the cytochrome P450 2E1 enzyme, resulting in an increase in reactive oxygen species and free radicals, thus leading to oxidative damage and necrosis of liver cells (61)

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Nitrite attenuates mitochondrial impairment and vascular permeability induced by ischemia-reperfusion injury in the lung

Histopathological analysis showed marked structural damage and inflammatory changes in the lung tissues of Hg-exposed rats, including epithelial disruption and increased infiltration of inflammatory cells

These often are intramuscular injections, which means that the needle targets muscle tissue and releases its contents there