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Selective serotonin reuptake inhibitors (SSRIs) are widely used to treat such disorders by inhibiting the reuptake transporter (SERT) that removes serotonin from the synaptic cleft, in turn increasing the gain of serotonin signaling in the brain

However, this was primarily the case for grade 3 disc degeneration (n = 3), where still strong statistical differences could be identified and for which the range of motion was generally very low in all three primary motion directions, as severe disc degeneration is usually associated with an immobilization of the motion segment due to very low disc height and bridging osteophytes (Fig

In addition, the infection can lead to the development of gastric mucosa-associated lymphoid tissue (MALT) lymphoma (Pereira and Medeiros, 2014)