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The Use of N-acetylcysteine supplementation to decrease irritability in four youths with autism spectrum disorders

An additional mechanism for the realization of the antioxidant effect of hydrogen is the effect on signal-regulating kinase-1 (ASK1) and the regulatory pathway of mitogen-activated protein kinase (p38-MAPK), which mediates the antioxidant activity of the compound and its anti-apoptotic properties [33]

[DOI] [PMC free article] [PubMed] [Google Scholar] 2.Abbasi J

In a double-blind controlled clinical trial, patients received 800 mg of NAC or placebo over the course of 16 weeks [78]

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