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Mechanistic link between vitamin B12 and Alzheimer's disease

In human embryonic stem cells (hESCs), the conserved lncRNA-FAST binds to the WD40 domain of the E3 ubiquitin ligase -TrCP, inhibiting the ubiquitination of -catenin by -TrCP, resulting in the accumulation of -catenin in the nucleus
Comparison of (R)-ketamine and lanicemine on depression-like phenotype and abnormal composition of gut microbiota in a social defeat stress model

m6A/IGF2BP3-driven serine biosynthesis fuels AML stemness and metabolic vulnerability

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