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Targeting of hematologic malignancies with PTC299, A novel potent inhibitor of dihydroorotate dehydrogenase with favorable pharmaceutical properties

Designed exclusively for research use, not for human consumption

used for the synthesis of fatty acids, cholesterol, steroids, isoprenoids, ketone bodies, and acetylcholine

We aimed to evaluate structural heart disease prevalence in a cohort of adult subjects with OI and its relationship with the severity of the disease and the COL1 genotype
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