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RNA-seq data mapping was processed using Spliced Transcripts Alignment to a Reference (STAR) method, as previously described ( 2.6.8.2 Differential expression and pathway-level data extraction The raw data for the EpiAlveolar experiments underwent QC

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UVVis absorbance was measured using UVVis spectrophotometer (Lambda 35, Perkin Elmer) to ensure the absence of large NPs, which commonly show absorption at about 520 nm