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1 Introduction Migraine manifests as a chronic neurovascular disease characterized by unilateral or bilateral throbbing severe headaches, predominantly unilateral, recurring with symptoms such as nausea, vomiting, photophobia, and phonophobia that impair autonomic nervous system functions (Steiner and Stovner, 2023) many sufferers cannot perform normal or work activities

The latter can be reduced by thioredoxin (Trx) 2, which is further reduced by thioredoxin reductase [28]

This drug comes with several precautions

Here are a few with mixed results

Vitamin deficiencies, such as low levels of folic acid, vitamin B12, or vitamin D, can impact erections and benefit from supplementation