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Furthermore, compared to the control group, there was a decrease in the percentage of CD45, a marker of microglial activation, in the cortex (above 18%) and the hippocampus (28%)

Vitamin E modulates inflammation by interacting with cyclooxygenase (COX) enzymes, which are responsible for the synthesis of prostaglandins at the site of inflammation (Schubert et al

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doi: 10.1139/h03-045 [DOI] [PubMed] [Google Scholar] [89].Cheng AJ, Jude B, Lanner JT

(ii) homocysteine is converted to methionine in the presence of methylcobalamin, which can be metabolized to S-methionine