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They not only aid in the weight loss process, but provide the body with much needed essential vitamins and minerals it is lacking

this approach may increase the likelihood of identifying potential index FH cases

Observations of saturable uptake supports the involvement of transporters in the uptake of fatty acids and cholesterol, but uptake after proteolytic treatment of the brush border membrane supports a role of passive diffusion as well

If patients are on a high-intensity statin, but not at the highest approved dose (i.e., on atorvastatin 40 mg or rosuvastatin 20 mg), increasing the dose further (i.e., to atorvastatin 80 mg or rosuvastatin 40 mg) is reasonable, but one should consider the minimal (6%) incremental LDL-C reduction with this uptitration as well as the dose-dependent nature of side effects of statins for patients at higher risk of such effects

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