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This is likely due to the role of vitamin B12 in energy production and metabolism

Incorporating vitamin B6 can help mitigate side effects such as nausea, stabilize mood, and support energy metabolism, while vitamin B12 is essential for preventing deficiencies, maintaining energy levels, and supporting neurological health

Stat3 Up-Regulates Expression of Nicotinamide N-Methyltransferase in Human Cancer Cells