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promote myocardial hypertrophy and fibrosis through the regulating the oxidation process of pyruvate and fatty acids, affecting cardiac energy metabolism and mitochondrial function, and accelerating the development of HF [113], these results suggest that TMAO may be a potential target for the treatment of HF

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11 BageshwarU.VerPlankL.BakerD.DongW.HamsanathanS.WhitakerN.et al (2016)

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