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Besides, thalidomide synergistically stimulated CD8 + T cells more than CD4 + T cells (Fu and Fu-Liu, 2002)
Dudziska E, Gryzinska M, Ognik K, Gil-Kulik P, Kocki J
It also is devastating proof of the power of todays amino acid, glutamine (Gln, Q) when proteins use it in excess in HD a trinucleotide repeat expansion causes too many Glns to be put in the huntingtin protein, leading to toxic protein being made
these are often termed phase I and phase II reactions, although the terminology is imprecise and it incorrectly implies a temporal order of the reactions
10.1038/nrn4019 43 BoboW
