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Leggio L., L'Episcopo F., and Magr A., Small Extracellular Vesicles Secreted by Nigrostriatal Astrocytes Rescue Cell Death and Preserve Mitochondrial Function in Parkinson's Disease, Adv Healthc Mater 11, no

54,59 This line sits 25% below the probable toxicity line. Studies have already shown that the treatment line (also known as the 150 line) serves well to identify and help protect high-risk patients who may already have diminishing APAP levels

Nature 496 , 238242 (2013)

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Future studies with comprehensive clinical assessments should further validate these findings